Case Series: Topical Cannabis Preparations Associated With Reduced Opioid Use

Toronto, Canada: The administration of whole-plant topical cannabis extracts is associated with reduced pain and opioid use in patients suffering from leg and ankle ulcers due to Pyoderma Gangrenosum (PG), according to a series of case reports published online ahead of print in the Journal of Pain Symptom Management.

Researchers from the University of Toronto evaluated the impact of topically applied cannabis extracts on skin ulcer wounds in three separate patients. Extracts contained nearly equal percentages of THC and CBD.

Investigators reported clinically significant analgesia and reduced opioid utilization in all three subjects.

“This is the first case series to demonstrate the potential of TMC (topical medical cannabis) to provide effective analgesia that was opioid sparing in the setting of PG,” authors concluded. “TMC has the potential to improve pain management in patients suffering from wounds of all classes.”

For more information, contact Paul Armentano, NORML Deputy Director, at: Full text of the study, “Topical medical cannabis: A new treatment for wound pain – Three cases of Pyoderma Gangrenosum,” appears in the Journal of Pain Symptom Management.”