Clinical Trial: CBD Dosing Associated with Transient Improvements in Sleep Satisfaction

São Paulo, Brazil: The administration of CBD is associated with temporary improvements in sleep satisfaction in patients with REM sleep behavior disorder (RBD), according to the results of a randomized, placebo-controlled study published in the journal Movement Disorders. Patients diagnosed with RBD experience violent arm and leg movements during REM sleep. These movements are typically associated with vivid nightmares,

Brazilian researchers compared the use of CBD versus placebo in a cohort of 33 patients with RBD and Parkinson’s disease. 

Compared to placebo, CBD administration at 300mgs was associated with temporary improvements in subjects’ average sleep satisfaction. However, CBD dosing was not associated with any significant reduction in patients’ RBD frequency.

Several prior studies have reported promising results for the use of either cannabis or cannabinoids to mitigate various sleep-related disorders, including insomnia, sleep apnea, and nightmares.

Full text of the study, “Cannabidiol for rapid eye movement sleep behavior disorder,” appears in Movement Disorders.