Study: CBD Administration Reduces Blood Pressure

oil_bottlesOral CBD administration is associated with reduced blood pressure in healthy volunteers, according to clinical trial data published online in the Journal of Clinical Investigation.

Investigators from the University of Nottingham in the United Kingdom assessed the effects of a single oral dose of 600 mg of CBD extract versus placebo in nine male subjects.

Cannabidiol administration reduced resting systolic blood pressure and stroke volume (the amount of blood pumped by the left ventricle of the heart in one contraction). Compared to placebo, CBD intake was associated with reduced BP levels following exercise and in response to stress. Increased heart rate was observed following CBD administration, but no “adverse events” were reported by participants either during or following the study sessions.

Authors concluded: “Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress, particularly cold stress, and especially in the post-test periods. This may reflect the anxiolytic and analgesic effects of CBD, as well as any potential direct cardiovascular effects. … Further research is also required to establish whether CBD has any role in the treatment of cardiovascular disorders such as a hypertension.”

Full text of the study, “A single dose of cannabisiol reduces blood pressure in healthy volunteers in a randomized crossover study,” is online here.

17 thoughts

  1. Trump and Sessions want to take away your cannabis, while Ryan and McConnell want to take away your health care. What’s to like about Republicans? Clearly, they despise us! Their answer to our health concerns: “Drop dead.”

  2. @ NORML,
    Thank you for giving me a chance to get a lot of things off my chest, things that have been pent up over a lifetime, in some cases.

    There is a rare sense of community I get from commenting on this blog, and I am grateful for the chance to participate in that. NORML blogs represent some of the most interesting, substantive, and personal conversations I can have.

    I know I get rude and crude when I talk about Trump and his Republican sheep. And, I can understand how that kind of “shock talk” might cross the line for some folks.

    However, let me say this: it must be done in order to prevent the normalization of Trump.

    To anyone who may be offended by the disrespectful and indecent ways I talk about Trump and the Republicans, I say the following:

    You absolutely cannot be less offended by Trump than by me. Where I am gross, Trump is profane. Where I use sexual language and metaphors, Trump assaults actual women (and for all I know, men.) Where I am a public nuisance, Trump is a threat to society. Where I am angry, Trump is violent. There is absolutely nothing I have said about Trump or the Republicans that isn’t eclipsed by the very real carnage and crimes that Trump and the Republicans are doing, even at this very moment.

    I would say to such an individual, one who might be offended by my comments about Trump, that if they are more offended by my rudeness to Trump than they are by Trump himself, then their indignation would certainly ring hollow to me.

    Puff puff pass!

    1. Mark,

      In light of all the abrasiveness coming from the right these days, I can only nod in satisfaction at your sometimes biting comments.

      Cons and GOPers have adopted a confrontational tone, often vicious, since the 1990s at least when Bill Clinton was prexy. I’ve encountered it personally and I’ve seen it many times on the TV talk shows. Even many GOPer Senators and Congressmen have adopted that abrasiveness; oftentimes, I believe, they are “performing” for their base.

      It unfortunately followed that said GOPer politicians extended that abrasiveness and confrontational attitude toward the workings of our government itself. They obstructed Obama for 8 years on nearly every single issue. Compromise was never in their lexicon. They seemed to care not if their obstruction hurt the American people. Everything to them was/is politics–everything.

      Even on this website (!!), we saw Cons and Liberts attack Obama, Pelosi and Reid endlessly, even mocking them when they supported our cause!! These people cared less about legalization than they did pure partisanship. It was Cons and Liberts also, primarily, who OPPOSED LEGALIZATION in California back in 2010, in Prop 19. They whined about everything in that bill; you couldn’t help but get the feeling that many of them were black marketeers intent on protecting their cash cow. People getting arrested for pot? They didn’t care.

      So no, Mark, I have no problem with you dishing a little bit of shit back in their direction. To them I say: you reap what you sow.

  3. Thank you Paul, as always, for collecting a library of data to prove to our state and federal Congress why whole plant marijuana is not only a powerful medicinal tool, but a great way to relax.

    And great work and data from your report in Alternet showing a reduction in alcohol consumption where marijuana is legalizing;

    I know for a fact that consuming marijuana early in the morning and at the end of my day not only helps me reduce my blood pressure and relax, but as an alternative to chugging more beers Im in s better mood when I get home to my family, Im not irritated and I can spend quality time with the people that I love.
    Sure I still drink a beer after a hard days work but its 1 or two quality craft beers, not a 12 pack like I would chug down before I had a steady supply of quality weed. The lesson is quality is better than quantity. And weed doesnt give you a hangover even after you moderate with water on poker night. Annie up alcohol; Pots right and almost legal.

    1. @ ROLAND,
      Believe it or not, the idea has occurred to me before… I just never went to the trouble of climbing a tree to plant one amongst the tree-tops… But helicopters with infrared might find it… I think the cannabis stands out, from the air… I would bet a dollar someone has tried it…

      1. The thing that stands out about cannabis is the leaf which more than any other (except maybe sweet gum tree) resembles human hand (Hand/Hanf) and no surprise, the plant “learned” over eons to ingratiate itself with humans by adopting that leafshape.
        For reference I’ll regurgitate the “Man’s Best Friend, Animal/Vegetable” tabulation:
        “Friend” dephoneticizes to “Free Hand”, figure it out.

      2. @Dain Bramage;
        My brothers and I tried growing weed up in trees several times, since we built our own tree houses… and I guarantee you the big threat wasnt the infared from the game warden (which we knew was most certainly there). The real threat were racoons. Sure, we eliminated deer. But think of whats left? Squirrels. Spider mites. Fucking anything… marijuana is THAT GOOD! There’s a reason why psychoactive and medical marijuana is grown indoors and industrial hemp is grown outdoors. Theyre called COONS! … damn coons… I bet they ENJOY it too!

      3. Please attend to bloodpressure and don’t overly curse the coons, they are the only species of inhuman animal that ever accepted a gift from me hand to hand! Coons regularly entered Warehouse 5 where I worked to steal catfood, and I held out small chunks of bread, pizza or fries which at first they took in the mouth and ran away, but once an individual got more trusting that I wouldn’t grab, they would bring both hands up (no opposable thumb), take the bread, stuff it in their mouth, then run! Reason apparently, they trusted their own hands to situate the chunk better in mouth so they wouldn’t drop it while running to a safe distant chewplace.
        No, I don’t have the finances to offer them any Weed edibles yet.

  4. Tests with CBD oil are proving to host a variety of benefits. It’s good that this can be used in lieu of medications with more harmful side effects. Thanks for sharing!

  5. I’ve been using hemp CBD products on my father who has cancer. After using water soluble BioCBDplus his blood pressure dropped to normal. It’s absolutely amazing that this has happened to him – Jennifer

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