The administration of THC modulates emotional processing in healthy volunteers, according to placebo-controlled crossover trial data published online by the journal European Neuropsychopharmacology. Researchers concluded: “These results indicate that THC administration reduces the negative bias in emotional processing. This adds human evidence to support the hypothesis that the endocannabinoid system is involved in modulation of emotional processing. Our findings also suggest a possible role for the endocannabinoid system in abnormal emotional processing, and may thus be relevant for psychiatric disorders such as major depression.”
Pulmonary complications associated with the regular smoking of cannabis are “relatively small” and far lower than those associated with tobacco smoking, according to a recent review published in the June edition of the scientific journal Annals of the American Thoracic Society. The paper – authored by Donald P. Tashkin, MD, emeritus professor of medicine and medical director of the Pulmonary Function Laboratory at the David Geffen School of Medicine at University of California, Los Angeles – is “the most comprehensive and authoritative review of the subject ever published.”
Researchers at West Virginia University assessed the impact of THC administration in an animal model of NSAID-induced gastric inflammation. Investigators reported that low doses of THC provided gastroprotective effects, significantly attenuating gastric hemorrhages and lesions. They concluded, “[C]annabinoids may have the added benefit of reducing the effective analgesic dose of NSAIDs, as well as reducing the incidence of NSAID-induced gastric ulcers.”
Oklahoma Gov. Mary Fallin has signed legislation, House Bill 1441, into law that criminalizes drivers from operating a motor vehicle if they have any detectable amount of THC and/or its inactive metabolites in their blood or urine. Under such internal possession statutes, known as zero tolerance per se laws, motorists who test positive for the presence of such compounds are guilty per se (in fact) of a criminal traffic safety violation, regardless of whether or not there exist supporting evidence that a defendant was behaviorally impaired by such compounds.
Preclinical study data published online in the scientific journal Nutrition & Diabetes reports that tetrahydrocannabivarin (THCV) — a naturally occurring analogue of THC — possesses positive metabolic effects in animal models of obesity. Researchers concluded: “Based on these data, it can be suggested that THCV may be useful for the treatment of the metabolic syndrome and/or type 2 diabetes (adult onset diabetes), either alone or in combination with existing treatments.”
Recent preclinical studies published over the past weeks provide further evidence that cannabinoids are both neuroprotective and cardioprotective.
A Michigan traffic safety law that prohibits the operation of a motor vehicle by persons who possess any presence of THC in their blood, regardless of whether or not they are behaviorally impaired by the substance, may not be strictly applied to state-qualified medical cannabis patients.